Half a King
by Joe Abercrombie

As a younger son born with a  crippled hand, Prince Yarvi never expected to be sitting on the black throne. But when his father and brother are killed, Yarvi is crowned and almost immediately betrayed. He will face attempted assassination, being sold into slavery, and countless threats to his life, but his oath to avenge the death of his father won't let Yarvi quit.

Tomorrow, and Tomorrow, and Tomorrow
by Gabrielle Zevin

"A modern love story about two childhood friends, Sam, raised by an actress mother in LA's Koreatown, and Sadie, from the wealthy Jewish enclave of Beverly Hills, who reunite as adults to create video games, finding an intimacy in digital worlds that eludes them in their real lives, from the New York Times best-selling author of The Storied Life of A.J. Fikry"

Me Before You
by Jojo Moyes

Taking a job as an assistant to extreme sports enthusiast Will, who is wheelchair bound after a motorcycle accident, Louisa struggles with her employer's acerbic moods and learns of his shocking plans before demonstrating to him that life is still worth living. By the author of The Last Letter from Your Lover.

Flowers for Algernon
by Daniel Keyes

Charlie Gordon is about to embark upon an unprecedented journey. Born with an unusually low IQ, he has been chosen as the perfect subject for an experimental surgery that researchers hope will increase his intelligence-a procedure that has already been highly successful when tested on a lab mouse named Algernon. The experiment appears to be a scientific breakthrough of paramount importance, until Algernon suddenly deteriorates. Will the same happen to Charlie?

Wonder
by R. J. Palacio

Born with a facial deformity that initially prevented his attendance at public school, Auggie Pullman enters the fifth grade at Beecher Prep and struggles with the dynamics of being both new and different, in a sparsely written tale about acceptance and self-esteem.

The Kiss Quotient
by Helen Hoang

A 30-year-old math whiz with Asperger's tries to make her love life as rich as her career by hiring an escort to help her with her lack of knowledge and experience in the dating department. 

Keeping Lucy
by T. Greenwood

Forced by her powerful in-laws to institutionalize a daughter born with Down Syndrome, a grieving mother turns fugitive in the wake of harrowing discoveries about her daughter's hospital. 

The Curious Incident of the Dog in the Night-Time
by Mark Haddon

After stumbling upon his neighbor's dog, Wellington, impaled on a garden fork and being blamed for the killing, fifteen-year-old Christopher John Francis Boone, an autistic savant obsessed with Sherlock Holmes, decides to track down the real killer and turns to his detective hero to help him with the investigation, which brings him face to face with a family crisis.

Starless
by Jacqueline Carey

Trained as an elite warrior before learning a profound truth about his identity, Khai navigates the deadly intrigues of court before embarking on a quest to save his soul's twin. 

The Diving Bell and the Butterfly
by Jean-Dominique Bauby

In 1995, Jean-Dominique Bauby was the editor-in-chief of French Elle, the father of two young childen, a 44-year-old man known and loved for his wit, his style, and his impassioned approach to life. By the end of the year he was also the victim of a rare kind of stroke to the brainstem.  After 20 days in a coma, Bauby awoke into a body which had all but stopped working: only his left eye functioned, allowing him to see and, by blinking it, to make clear that his mind was unimpaired. Almost miraculously, he was soon able to express himself in the richest detail: dictating a word at a time, blinking to select each letter as the alphabet was recited to him slowly, over and over again. In the same way, he was able eventually to compose this extraordinary book.

How to Walk Away
by Katherine Center

When an accident on what was supposed to be the happiest day of her life lands her in the hospital with a very uncertain future, Margaret struggles to come to terms with family secrets, heartbreak and starting over before discovering love in an unexpected place. 

All the Light We Cannot See 
by Anthony Doerr

A blind French girl on the run from the German occupation and a German orphan-turned-Resistance tracker struggle with respective beliefs after meeting on the Brittany coast

One Two Three
by Laurie Frankel

Mab, Monday, and Mirabel have the misfortune of being born in Bourne, a town ravaged by the Belsum chemical company owned by the Templetons, a family who is indifferent to the birth defects and untimely deaths the effluence from their factory have caused. Mab seems to have escaped the worst of it, but Monday is clearly neurodivergent, and Mirabel has a brilliant mind trapped in a body that does not allow her to speak, move, or breathe comfortably without support. Their mother does triple duty keeping the tattered class action lawsuit alive, providing counseling by day and slinging beers at the local tavern at night. The sudden reappearance of the Templeton family brings their youngest heir, River, to a town that is openly hostile, even as his father begins a campaign to revive the business.

Five Feet Apart
by Rachael Lippincott

A teen on the waiting list for a lung transplant faces an impossible choice when her infection risks prevent her from getting within five feet of the boy she loves, a fellow patient who is determined to experience life outside the hospital. Movie tie-in. Simultaneous eBook.

True Biz
by Sara Novic

Taking readers into a residential school for the deaf, this coming-of-age novel follows three people; a rebellious transfer student, the school's golden boy and the headmistress as they each deal with personal and political crises and find their lives inextricable from one another.

The Memory Keeper's Daughter
by Kim Edwards

In a tale spanning twenty-five years, a doctor delivers his newborn twin daughter during a snowstorm and, rashly deciding to protect his wife from the baby's affliction with Down Syndrome, turns her over to a nurse, who secretly raises the child. 

Get a Life, Chloe Brown
by Talia Hibbert

Emerging from a life-threatening illness, a fiercely organized but unfulfilled computer geek recruits a mysterious artist to help her establish meaning in her life, before finding herself engaged in reckless but thrilling activities. 

How Lucky
by Will Leitch

Unable to speak or move without a wheelchair, Daniel, spending hours observing his neighborhood from his front porch, believes he has witnessed the kidnapping of a young college student and vows to solve this mystery. 

Love Anthony
by Lisa Genova

Two women in Nantucket, dealing with their own separate issues of death and heartbreak, find solace in each other's friendship

Gallant
by Victoria Schwab

Invited to return to Gallant, Olivia Prior finds herself in a crumbling manor riddled with secrets about her family, forcing her to decide whether to protect our world against the Master of the House or take her place beside him. 

The Cuckoo's Calling
by Robert Galbraith

Working as a private investigator after losing his leg in Afghanistan, Cormoran Strike takes the case of a legendary supermodel's suspicious suicide and finds himself in a world of multi-millionaire beauties, rock-star boyfriends, desperate designers and hedonist pursuits. 20,000 first printing.

Love from A to Z
by S. K. Ali

Suspended for standing up against a teacher's hate speech, a Muslim teen visits her aunt in Qatar, where she bonds with a motherless young man who is attempting to hide his multiple sclerosis diagnosis from his grieving father. 

Handle with Care
by Jodi Picoult

Struggling with their baby's illness, Charlotte and Sean O'Keefe work through their initial heartbreak and the pitying stares of other parents by spending time with little Willow, who proves remarkable and forces her parents to reevaluate their ideas about what they might have chosen for their family.

Fortune Favors the Dead 
by Stephen Spotswood

In 1945 Manhattan, Lillian Pentecost, “the most famous woman detective in the city and possibly the country,” struggles with multiple sclerosis. Fortunately, Lillian can always rely on her sharp-witted assistant, Willowjean Parker. Lillian hired her three years earlier after Will, a runaway whose five years performing with a traveling circus gave her a unique skill set, used her knife training to save Lillian’s life from a gunman. Their latest case involves a wealthy woman who was bludgeoned to death with a crystal ball in a locked room during a party.

So Lucky
by Nicola Griffith

A novel based on the author's life follows the experiences of a committed martial artist and manager of a successful charity foundation whose illusions are completely shattered by the realities of living alone with an autoimmune disorder. 

Romancing the Duke
by Tessa Dare

Although Isolde Ophelia Goodnight's father made a fortune as the author of the bestselling series of novels that immortalized her as "Little Izzy Goodnight," he died without a penny to his name, leaving Izzy destitute and homeless. An inheritance from her godfather in the form of Gostley Castle proves a welcome surprise, even if a more appropriate name for the crumbling ruin is "ghostly" or "ghastly." Its current occupant, Lord Ransome Vane, the blind, brooding Duke of Rothbury, is considerably less charming...and unwilling to surrender his claim to the castle.

A Curse so Dark and Lonely
by Brigid Kemmerer

A lush retelling of Beauty and the Beast finds a cursed prince reliving the same autumn over and over in the form of a dangerous monster, hoping to save his kingdom and win the heart of a girl from the real world. By the author of the Elementals series.

The Shining 
by Stephen King

Jack Torrance sees his stint as winter caretaker of a Colorado hotel as a way back from failure, his wife sees it as a chance to preserve their family, and their five-year-old son sees the evil waiting just for them.

Lock In
by John Scalzi

When a new virus causes one percent of the population to become completely paralyzed in body but not in mind, America pursues a scientific initiative to develop a virtual-reality world for victims, with unexpected consequences.